Washington, District of Columbia 2021-09-28 13:29:28 –
September 28, 2021
For researchers around the world working to understand and treat Alzheimer’s disease and ultimately find a cure, data from laboratory tests of patients suffering from this complex neurodegenerative disease are standardized and accessible. Must be. Since 1999 it has been National Alzheimer’s Disease Coordination Center (NACC) is housed in the Epidemiology Department of the UW School of Public Health and does this.
The UW Center, funded by the National Institutes of Health at NIH, has begun collecting data from another set of centers in hospitals and clinics across the country. These centers, Alzheimer’s Disease Research Center(ADRC), Currently, that number has increased to 35. UW Medical ADRC — And the data they provide has grown as well, from clinical diagnostics to scans of brain, neuropathology, and genomics.
Earlier this summer, the National Institute on Aging promised $ 35 million to continue funding the National Alzheimer’s Coordination Center at the University of Washington until 2026.
“We have data on about 44,000 individuals, as well as neuropathological examinations and imaging data on about 6,000 people,” he said. Walter Kukuru, Director of the University of Washington Center and Professor of Epidemiology. “It also links to most of the subject’s genomics data. We distribute the data to researchers around the world for free, so about 1,400 research publications have been published.”
Kukull said his team began working with NIA and clinical leaders across the country a few years ago to develop a more detailed, long-term standardized approach to collecting data.
“Around 2002, we implemented a standardized collection system for neuropathological data. Then, in 2005, we worked with all ADRCs and NIAs to provide standardized clinical testing and primary data collection across all ADRCs. We have implemented it, “says Kukull. “that is Unified dataset.. It is still valid today and has begun a fourth revision to keep scientific and clinical practices up to date. “
NACC staff and faculty will help coordinate national meetings with all centers, collect and maintain data, guide researchers’ questions through the data, and refine hypotheses.
“Requesters are usually referred to one of the consulting research professionals who are pointing the right direction,” says Kukull. “We can help researchers download the entire set, but also focus on what they want to do, the questions they are investigating, and the data they want to download. We are also working to make this process more “self-service” and make it easier for researchers to see and access the data. “
Kukull said the new grant will help move vast amounts of data, including over 20 years of large image files and voice recordings, collected in neuropsychological tests to the cloud. We will also continue to enhance the software capabilities for processing this big data, including increased involvement in machine learning.
“Alzheimer’s disease is a complex disease with a variety of disorders,” says Kukuru. “Alzheimer’s disease as a brain disorder does not occur on its own. For example, how it interacts with cognitive decline and dementia symptoms such as vascular disease, minor strokes, Lewy body dementias, and Parkinson’s disease. Is one of the big problems that everyone is struggling with. “
NACC, ADRC, and NIA are focused on advancing research as much as possible to find a cure or cure for Alzheimer’s disease by 2025. this is, National Alzheimer’s Disease Project Law The law was signed by President Obama in January 2011.
“Publishing data to a place where people can access it and see it in other ways that perhaps no one thought of it is an important part of achieving that goal,” Kukul said. Says.
tag: Alzheimer’s Disease Research Center •• Faculty of Epidemiology •• National Alzheimer’s Disease Coordination Center •• Population health •• Faculty of Public Health •• UW medicine •• Walter Kukuru
Alzheimer’s data center at UW awarded $35 million to continue mission of free, global access Source link Alzheimer’s data center at UW awarded $35 million to continue mission of free, global access