Cannabis-derived drug reduces symptoms for local woman suffering chronic seizures – Seattle, Washington

Seattle, Washington 2021-07-17 08:00:00 –

When Kerry Fox, a 27-year-old Bellevue woman, was eight months old, she was diagnosed with a rare neuropathy called tuberous sclerosis.

This disorder (TSC) causes non-cancerous tumors to grow in the brain and other important organs, causing seizures and developmental disorders.

Kelly’s early life was challenging. According to her mother, Leslie Fox, her seizures began when she was four weeks old. Doctors told her that TSC patients are more likely to develop epilepsy and autism, with a life expectancy of 20 years.

Kerry Fox almost always had seizures. At the age of one, doctors told her mother that the seizures were blocking her brain development.

At the age of 12, her family had to make the difficult decision to allow surgery to remove most of the brain and amputate the other parts of the brain that were causing the seizures.

Fox’s mother remembers seeing her after the surgery and hearing her daughter say, “Mom, my head hurts,” one of the biggest constructs I’ve ever said.

Leslie Fox knew that surgery would have a big impact on the moment and was hopeful about what Kelly could do after that.

After learning how to walk and crawl, Kerry Fox began riding and swimming. However, she was still suffering from intermittent seizures. Eventually, Kelly qualified for a clinical trial of the cannabis-derived drug Epidiolex, which aims to reduce seizures.

Leslie Fox noticed the difference between day and night in the amount of seizures her daughter experienced during the trial. Based on the results, she had the intuition that Kelly wasn’t in the placebo.

Kelly was able to sleep better because she had fewer seizures at night. She was able to communicate better and make friends in ways she couldn’t do before.

“Seizure control allowed her to begin the next chapter in her life,” said Leslie Fox.

Kelly was finally able to move to an adult family home with the help of her family. There you have your own space, your daily life, your neighbors and your friends.

“It was exciting to see her independence,” Leslie said. “It was important.”

Cannabis as a drug for seizures

Michelle Xston, a naturopathic doctor with a background in cannabinoid pharmacology, said cannabis has a long history of being used as a drug for seizures in Europe in the 1800s and perhaps in India for a longer period of time.

According to Sexton, the active ingredient in Epidiolex is almost 100% CBD, a non-psychoactive compound found in cannabis that is commonly used to reduce inflammation and anxiety.

She doesn’t fully understand why CBD has been shown to be so effective in controlling seizures, but it could be related to how it interacts with neurons in the brain. He said it was highly sexual.

Seizures occur when neurons in the brain that communicate with electrical signals have seizures that overwhelm the nervous system.

Sexton said the theory behind CBD’s effectiveness in reducing seizures is that it works by “reducing nervous system excitement.”

Cannabis-derived drug reduces symptoms for local woman suffering chronic seizures Source link Cannabis-derived drug reduces symptoms for local woman suffering chronic seizures

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