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Cardiac defects do not increase the risk of severe COVID

By Robert Preidt
Health Day Reporter

Friday, October 16, 2020 (HealthDay News)-Comes as relief news for people born with heart defects, a new study shows that these people are at high risk of moderate or severe COVID-19 I found that it wasn’t.

The study included more than 7,000 adults and children born of heart defects (congenital heart disease), followed by researchers at Columbia University Vagelos College in New York City.

Between March and July 2020, the Center reported 53 patients with congenital heart disease with COVID-19 infection (median 34 years).

“At the beginning of the pandemic, many were afraid that congenital heart disease would be as great a risk factor for COVID-19 as adult-onset cardiovascular disease,” the study author said on October 14. I am writing in a report published online. Journal of the American Heart Association..

However, the researchers were “relieved by the small number of patients treated at their center and their outcomes,” they said in a journal news release.

Of 43 adults and 10 children with COVID-19-infected congenital heart disease, 58% have complex congenital anatomy, 15% have hereditary syndrome, 11% have pulmonary hypertension, and 17% are obese. did.

According to the study, 9 patients (17%) suffered from moderate / severe infections and 3 patients (6%) died.

Simultaneous genetic syndromes in patients of all ages and advanced physiological stages in adult patients were each associated with an increased risk of severity of COVID-19 symptoms, the findings showed.

Five patients have trisomy 21 (extra chromosome 21), four patients have Eisenmenger’s syndrome (abnormal blood circulation caused by structural defects in the heart), and two patients have DiGeorge syndrome (22). Had a condition) caused by the deletion of a segment of chromosome 22). Almost all patients with trisomy 21 and DiGeorge syndrome showed moderate / severe COVID-19 symptoms.

According to Dr. Matthew Lewis of Columbia University Irving Medical Center and his colleagues, “Our sample size is small, but these results are sufficient cause of severe COVID-19 infection with certain congenital heart lesions alone. It means that it may not be. “

“Despite evidence that adult-onset cardiovascular disease is a risk factor for COVID-19 patients and worsening patient outcomes. [congenital heart disease] Adults who do not have an associated genetic syndrome and are not at an advanced physiological stage do not appear to be disproportionately affected, “the study authors conclude.

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