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CDC investigating 109 unusual hepatitis cases in kids in outbreak – Boston, Massachusetts

Boston, Massachusetts 2022-05-06 13:30:41 –

TThe Centers for Disease Control and Prevention said Friday that it was investigating 109 reported cases of abnormal hepatitis in previously healthy infants. Eight of them required liver transplantation and five died. Cases have been reported in a total of 25 states and territories.

Half of the children confirmed adenovirus infection, which is the current major and suspected cause of these illnesses. However, the CDC warned that the investigation was in its infancy and premature to reach a conclusion.

More than 300 such cases have been reported in more than 20 countries, according to figures drawn from the CDC. European Disease Control CenterAnd the UK Health and Security Agency (UKHSA).

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The phenomenon is First observed It occurred in Alabama last October, but became widely noticed worldwide in early April when UKHSA warned the world about a strange number of cases of hepatitis in very young children. .. Some patients are 16 years old, but most are under 5 years old. According to the CDC, the median age of cases in the United States is 2 years.

UKHSA reported on Friday that the number of cases had increased to 163 children, dating back to January 1. Eleven of the British children needed a liver transplant but have not died to date.

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Hepatitis is rare in very young children. Such cases where the obvious cause is not clear are even rarer. This condition (liver inflammation) can be caused by exposure to many pathogens and toxins, some medications, and misuse of alcohol. However, in most cases it is due to the hepatitis virus labeled A through E. These cases have been excluded and are currently classified as hepatitis of unknown etiology or cause.

The allegations focus on the type 41 adenovirus found in many children. More children in multiple countries have more commonly tested positive for adenovirus. In some cases, the sample is insufficient to run a test to try to type what type of adenovirus is present, but in other cases, work is still underway. However, other hypotheses are being considered. It may be a combination of various factors, for example, Covid-19 may have been caused by a previous infection with another virus such as SARS-CoV-2. They get more sick when they get infected with adenovirus.

In fact, UKHSA said Friday that it revised its working hypothesis.

“The main hypothesis remains that it contains adenovirus,” he said. Technical briefs Published online. “But we continue to investigate the potential role of SARS-CoV-2 and are working to eliminate the toxicological component.”

There is at least one exclusion by public health authorities. They are convinced that this phenomenon is not related to the Covid-19 vaccine. Most of the affected children are too young to be vaccinated. The Covid vaccine is not approved for use in children under the age of 5, which accounts for 75% of UK cases.

“Less than five elderly cases have been recorded to have been vaccinated with Covid-19 before the onset of hepatitis,” the UKHSA report said. “There is no evidence of a link between Covid-19 vaccination and acute liver syndrome.”



CDC investigating 109 unusual hepatitis cases in kids in outbreak Source link CDC investigating 109 unusual hepatitis cases in kids in outbreak

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