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CDC Panel recommends Pfizer boosters for children ages 5-11

The Centers for Disease Control and Prevention on Thursday said Pfizer Covid to children aged 5 to 11 years at least 5 months after the first vaccination series, as infections increased nationwide and immunity from the first two doses weakened. Booster shots are recommended.

The CDC’s panel of independent vaccine experts overwhelmingly agreed with boosters for children of that age group after reviewing and discussing the data at a five-hour public meeting. Dr. Rochelle Walensky, director of the CDC, approved the recommendations late in the evening, giving pharmacies, clinics, and other healthcare providers a green light to begin managing shots.

The CDC deploys boosters for children aged 5 to 11 years, even though most children have not yet received the first two doses and only 29% of the age group is fully vaccinated. doing. In a statement Thursday, Wallensky tried to reassure his parents that the shot was safe and recommended that the children be vaccinated.

“Primary series vaccinations in this age group lag behind other age groups and are susceptible to serious illness,” Warensky said. “I encourage parents to keep their children up-to-date with CDC’s COVID-19 vaccine recommendations.”

Covid is generally less severe in children than in adults, but more than at any other time during the pandemic, children aged 5 to 11 years are hospitalized during the Omicron wave. According to CDC data. Since the beginning of the pandemic, more than 4.8 million children in this age group have been infected with Covid and more than 15,000 have been hospitalized, according to CDC data.

Public health officials also said that children are long covid Multisystem inflammatory syndromeMIS-C for short, a serious condition associated with Covid infection that affects multiple organ systems.

“The impact and severity of long-distance Covid on children is significant and may not be seen in the medical setting, but it has an absolute impact on the lives of affected individuals,” said the chairman. Dr. Grace Lee said. He is a professor of pediatrics at Stanford University School of Medicine.

Since the onset of the pandemic, more than 8,000 children have developed MIS-C, and in 46% of reported cases, children aged 5 to 11 years are most commonly affected. According to CDC data.. It is reported that 16 children in the age group died from MIS-C, and 23% of the total of 68 died in children of all ages.

Dr. Cape Talbot, the only vote against the recommendation, said the United States has resources to vaccinate the overwhelming majority of children in the age group who have not received the first shot, rather than moving forward with booster shots. Said that it was necessary to concentrate.

Talbot, an infectious disease specialist and infectious disease specialist at Vanderbilt University, said:

According to CDC data, the United States currently reports an average of over 99,000 new infections per day as of Tuesday, an increase of 22% over the previous week. Hospitalizations have also increased by 22% over the past week, with data showing that an average of more than 3,000 people are infected with Covid daily.

As the number of cases increased, the immune protection provided by the vaccine against infection diminished over time after people obtained the primary vaccination series. Omicron and its submutants are also good at avoiding antibodies that block infection.

According to CDC data, in the 5-11 year old group, Covid vaccination was 43% effective against infection 59 days after the second dose during the period when Omicron became the major Covid variant. However, vaccination was 74% effective in preventing hospitalization for ages 5-11 for all viral variants.

Pfizer presents data from a small group of 30 children aged 5 to 11 years, with the third dose increasing 22 times the blocking antibody level against Omicron at 1 month post-dose compared to the second dose. Showed that it increased to. Dr. Charu Sabharwal, director of clinical research on vaccines at Pfizer, said elevated antibody levels should provide real-world protection against Omicron variants, although they did not provide efficacy data at Thursday’s meeting.

Sabharwal stated that among the larger group of 401 children, most responses to the third dose were mild to moderate, with fatigue and headache being the most common. The rate of fever was low, with no children reporting temperatures above 104 degrees Fahrenheit (40 degrees Celsius). There was no myocarditis, pericarditis, or heart inflammation. According to Pfizer data, 10 children had swollen lymph nodes, but the cases were mild and resolved within a week of onset.

Since the two-dose series was approved for the age group in November, more than 18 million Pfizer doses have been given to children aged 5 to 11 years in the United States. According to CDC data, the overwhelming majority of responses to vaccines, 97%, were not serious. The most common side effects of shots were fever, vomiting, headache, dizziness and malaise.

Myocarditis after the second Pfizer shot is rare in boys aged 5 to 11 years, with 2.7 cases reported per million doses. This is far less than boys aged 12 to 15 years who reported 48 cases of myocarditis per million doses. According to data from the CDC’s Vaccine Adverse Event Reporting System.

CDC official Dr. Sara Oliver said the incidence of myocarditis in children aged 5 to 11 years is likely to be even lower after booster immunization, as in other age groups. Said.

The CDC identified 20 cases of myocarditis, an inflammation of the heart, in children aged 5 to 11 years as of April after Pfizer vaccination. The overwhelming majority of myocarditis patients were boys, 17 were hospitalized and one died. The deceased boy had no evidence of viral infection and had a fever 12 days after administration 1, followed by abdominal pain, vomiting and death on day 13.

CDC, In a large study published in AprilWe have found that there is a higher risk of myocarditis after Covid infection than vaccination with Pfizer and Moderna shots.

CDC Panel recommends Pfizer boosters for children ages 5-11

Source link CDC Panel recommends Pfizer boosters for children ages 5-11

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