By Robert Preidt
Health Day Reporter
Thursday, November 19, 2020 (HealthDay News)-The COVID-19 vaccine under development at Oxford University in the United Kingdom appears to be safe and causes an immune response in the elderly, researchers report.
Because older people are at increased risk of COVID-19, it is important that vaccines against this disease are effective in this age group.
“The immune response from vaccines often declines in older people because their immune system gradually deteriorates with age, which makes them more susceptible to infections,” said Andrew, the author of the study at Oxford University.・ Professor Polard said.
“As a result, it is important to test the COVID-19 vaccine in this group, which is also the priority group for vaccination,” he said in a news release from the journal. Lancet..
A phase II trial of the ChAdOx1 nCoV-19 vaccine included 560 healthy adults, including 240 over 70 years of age.
Vaccines have been found to cause few side effects, are more tolerated by older people than younger adults, and cause similar immune responses across age groups.
Both low-dose and standard-dose vaccines evoked reactions in both parts of the immune system. The T cell response occurred within 14 days of the first dose of vaccination and the antibody response occurred within 28 days of the additional dose of vaccination.
“The strong antibodies and T-cell responses found in older people in our study are encouraging,” said Dr. Mahesi Ramasamy, also co-author at Oxford University.
“The highest risk of serious COVID-19 infection is in people with pre-existing health and the elderly, although we hope our vaccine will help protect the most vulnerable people in society. We need more research before us. We can certainly do it. “
The study was published on November 19th Lancet..
The immune response reported in this study does not prove that the vaccine protects against coronavirus infection. Phase 3 trials are currently underway to determine the efficacy of the vaccine against the disease.
For more information
For more information on the COVID-19 vaccine, please visit the US Centers for Disease Control and Prevention.
Source: Lancet, News Release, November 19, 2020
Data show that Oxford COVID vaccine is safe and effective
Source link Data show that Oxford COVID vaccine is safe and effective