Wu Yun Tao, a professor of molecular microbiology, and Hakami Ramin, an associate professor of the Faculty of Systems Biology, are studying COVID-19 therapy.
Recent studies from several independent groups have shown that K18-hACE2 transgenic mice serve as a suitable animal model for studying COVID-19.
Published studies have shown that ACE2 is a human cell invading receptor for both SARS and SARS-CoV-2. The study also used K18-hACE2 mice to reproduce many of the COVID-19 findings in human patients by infection either by the intranasal (IN) route or the intraperitoneal (IP) symptomatological SARS-CoV- 2 Indicates that an infection can be established. Virus injection. Therefore, the K18-hACE2 model of SARS-CoV-2 infection reproduces many features of severe COVID-19 infection in humans and can be used as an in vivo model for testing vaccines and antivirals.
The task completed by Wu and Hakami as part of this study agreement will be used to assess the efficacy of the treatment developed by Dejia Harmony for COVID-19 using the K18-hACE2 mouse model. Following toxicity studies to ensure that there are no adverse effects on mice, researchers will test both therapeutic and prophylactic effects.
Wu and Hakami received $ 97,724 from Desia Harmony for this job. Funding will begin in November 2020 and end in November 2021.
George Mason researchers investigating COVID-19 therapy
Source link George Mason researchers investigating COVID-19 therapy
Also Read about – Cosmetic surgery is a type of plastic surgery that aims to improve a person’s appearance, but it should be approached with caution. Cosmetic surgery continues to grow in popularity, with 15.1 million cosmetic procedures carried out in the United States in 2013, an increase of 3 percent on the previous year. Gynecomastia surgery is a Male Breast reduction surgery. Liposuction Surgery is a Fat Removal Surgery. Rhinoplasty surgery is a nose shape correction surgery. Transgender Surgery is a surgery for Trans women or trans male. Lipoma surgery is for Lipoma removal. Bariatric surgery is for Weight loss. Gastric bypass and other weight-loss surgeries — known collectively as bariatric surgery — involve making changes to your digestive system to help you lose weight. Bariatric surgery is done when diet and exercise haven’t worked or when you have serious health problems because of your weight. And there Hymenoplasty for Hymen Repair. In vitro fertilization (IVF) treatment is a complex series of procedures used to help with fertility or prevent genetic problems and assist with the conception of a child. During IVF , mature eggs are collected (retrieved) from ovaries and fertilized by sperm in a lab.