People with heart failure may be at increased risk of cancer.
Cancer patients are usually monitored for heart failure because some anticancer drugs can damage the heart. Currently, new studies suggest that patients with heart failure who may live in this condition for years may benefit from being monitored for cancer.
The researchers used the German Health Database to track 100,124 patients with heart failure and compare them to the same number of controls without heart failure. Initially all cancer-free, scientists tracked the incidence of cancer over the next decade.The· The study is in the journal ESC Heart Failure..
Researchers lacked data on socioeconomic conditions, smoking, alcohol consumption, and physical activity that are known to affect cancer risk, but the two groups were age, gender, age, and obesity. , And the incidence of diabetes were consistent.
Nevertheless, the difference in cancer incidence between the two groups was significant. Overall, 25.7% of patients with heart failure were diagnosed with some form of cancer, compared with 16.2% of patients with heart failure.
Although other studies have seen an increase in the incidence of cancer in patients with heart disease, the large number of samples in this analysis allowed researchers to notice different types of cancer. Patients with heart failure were more than twice as likely to have cancer of the lips, mouth, and pharynx. The risk was 91% higher for lung cancer and other respiratory cancers, 86% higher for female genital cancers, and 83% higher for skin cancers. People with heart failure had a 75% higher risk of colon cancer, stomach cancer, and other cancers of the digestive system. Women with heart failure had a 67% higher risk of breast cancer and men had a 52% higher risk of genital cancer.
“I think this is an interesting retrospective cohort study,” said Dr. Girish L. Kalra, Senior Cardiology Fellow, David Geffen School of Medicine, UCLA. “The main drawback of this study is that the database did not allow researchers to manage smoking, which is the only greatest risk of developing cancer and heart disease. In this study, smoking is a common thread. There is a possibility.”
Nevertheless, a strong association with oropharyngeal and respiratory cancers suggests that smoking may be one explanation, but the association remains strong for a wide range of cancers. was. The study also managed various other cancer-related factors, such as obesity, diabetes, and aging, and the frequency of medical consultations that could lead to increased detection of cancer.
In addition to smoking, there are other possible mechanisms that can explain the link. For example, previous studies have found that well-known protein biomarkers of heart disease that appear before symptoms develop also correlate with an increased risk of cancer. Researchers write that chronic inflammation may be involved in both heart failure and cancer. Alcohol use is also associated with a variety of cancers.
“There are more correlations between heart failure and cancer than there are common risk factors,” said Mark Ludo, senior author of the University of Kiel’s cardiologist in Germany. “Heart failure is not a disease of the heart. It is most often a disease of the heart and other organs. The importance of comorbidities to the prognosis and quality of life of affected people cannot be overestimated.”
Dr. Kara agreed. “Ultimately, the heart is the bell of all health,” he said. “This study supports the idea that people with heart failure are a high-risk group and we need to pay the most attention. As a doctor, heart disease patients are screened for cancer at recommended time intervals. You need to make sure that you are receiving it, and we should continue to quit smoking for smokers. “
Heart Failure Is Linked to Increased Risk of Cancer, Research Results
Source link Heart Failure Is Linked to Increased Risk of Cancer, Research Results