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Is my immunity waning? Doctors advise Pfizer vaccine recipients not to worry – New Orleans, Louisiana

New Orleans, Louisiana 2021-10-11 13:31:00 –

There is little doubt that people’s immunity begins to weaken just months after completing the two-dose series of Pfizer COVID-19 vaccines. Vaccination creates a strong immune response, reduces the risk of serious illness by more than 90%, and gradually reduces protection against mild, asymptomatic infections. As a result, Pfizer has sought and received approval from the Food and Drug Administration to add boosters to many people. I’m 6 months after vaccination, do other people need to look for boosters? Dr. Ann Forsy, an expert on viral respiratory disease at the University of Rochester, said, “How worried should people be?” I think immunity slowly declines over time, which is why people panic. Not. ” “It’s not as sudden and complete as it was before vaccination,” added Falsey, who helps lead clinical trials of the COVID-19 vaccine. — Pfizer, Modana, Johnson & Johnson — for severe illness, ”Falsey told CNN. “Now, it’s not that we may not eventually reach the point where we need to get boosters to prevent more serious illnesses, but in reality, breakthrough infections. Most are colds and can be flu-like illnesses, she added, “the horrific illness we had faced before.” “So my main message, don’t panic. You’ll be fine.” Last week, more people were getting booster shots than getting the first round of coronavirus vaccine. By Friday, either more than 7 million Americans were either booster shots or a third round of vaccine approved for immunocompromised people who were likely not responding adequately to the first two shots. I received. Pfizer’s vaccine reduces immunity. A study in Israel included 4,800 health care workers, with antibody levels dropping rapidly after two vaccinations, “especially among men, people over the age of 65, and people with immunosuppression.” Was shown. A second study in Qatar showed that protection from the Pfizer vaccine peaked in the first month after vaccination and then began to decline. For a new wave of fashion, “the team wrote in a report published in the New England Journal of Medicine. Do you develop mild or asymptomatic infections while remaining strong against severe illness? That’s because the human immune system is complex. Antibodies form the first line of defense and prevent the virus from invading some cells in the body. This is a protection that begins to wear over time. But there is a second line of defense-cell-based immunity. Cells called B cells and T cells, which may take longer to produce than antibodies, provide a longer lifespan and broader protection against infections and are involved in reducing severe infections. If you get vaccinated, you are much less likely to get really sick, go to the hospital, or die. But there are many reasons why people don’t want to get sick. They don’t want to give it to their loved ones. People don’t want to give it to infants who haven’t been vaccinated yet. ” Mask around many other people who may or may not be vaccinated, especially indoors, when making sure the room is well ventilated, the FDA from both Moderna and Johnson & Johnson later this month. Cine is considering an application to approve vac booster administration. Dr. Anthony Fauci, director of the National Institute of Infectious Diseases, said he believes that a third dose of the vaccine will be part of the standard regimen for COVID-19. “People with boosters should have been vaccinated first in January, February and March. People over the age of 65, adults at risk of severe illness, higher than average It includes people in occupations and living conditions at risk of infection. Others need to cool it for now. “They don’t need it. They attack the pharmacy and panic.” People should not be willing to receive boosters, as they will not get the best immune response if six months have not passed since the last dose of the Pfizer vaccine, Forch said in White. “For example, recently vaccinated people will be tempted not to wait for six months,” he said at a house briefing last month. However, waiting a few months after the initial immunization to boost will help generate a stronger response. Immune system cells that help restore a weakened immune system respond more strongly if allowed to enter dormancy after the first vaccination. That said, most people should plan to get a booster in the end. Any vaccine, not just Pfizer, will benefit from boosting immunity. It’s not the same as saying it’s very necessary, “she said. “I feel like I’m a strong person, so I think it’s like playing Russian roulette, depending on my natural immunity,” Forsy said. -19 And then he died. “I would never rely solely on my natural immunity to survive this virus. It’s a very, very bad actor,” Falsey said.

There is little doubt that people’s immunity begins to weaken just months after completing the two-dose series of Pfizer COVID-19 vaccines.

Two doses of the vaccine produce a strong immune response, reducing the risk of serious illness by more than 90%, but gradually reducing protection against mild, asymptomatic infections.

As a result, Pfizer has sought and received approval from the Food and Drug Administration to add boosters to many people who have been vaccinated for six months.

But should others also look for boosters? How much do people need to worry about?

Dr. Anne Forsy, an expert on viral respiratory disease at the University of Rochester School of Medicine, said:

“It’s not as sudden and complete as it was before vaccination,” added Falsey, who is helping to lead clinical trials of the COVID-19 vaccine.

“All vaccines work pretty well for serious illnesses such as Pfizer, Modana and Johnson & Johnson,” Forsy told CNN. “Now, it’s not that we may not eventually reach the point where we need to get boosters to prevent more serious illnesses, but in reality, breakthrough infections. Most are colds and can be flu-like illnesses. The horrific illnesses we have faced before, “she added.

“So my main message is, don’t panic. You’ll be fine.”

It didn’t stop Americans flocking to get boosters. Last week, more people were getting booster shots than they were getting the first round of coronavirus vaccine. By Friday, more than 7 million Americans were likely not responding adequately to the first two injections, a boost or a third licensed boost to immunocompromised people. I was vaccinated.

this week, Two more studies In addition to increasing evidence that Pfizer’s vaccine reduces immunity.

A study in Israel of 4,800 health care workers found that double vaccination of “especially men, people over the age of 65, and people with immunosuppression” resulted in a rapid decrease in antibody levels. Shown.

A second study from Qatar showed that protection from the Pfizer vaccine peaked in the first month after vaccination and then began to decline.

“These findings suggest that the majority of the vaccinated population may lose protection against infection in the coming months, possibly increasing the likelihood of a new wave of epidemics. The team wrote in a report published in the New England Journal of Medicine.

How can protection be weakened against mild or asymptomatic infections while remaining strong against severe illness?

Because the human immune system is complex.

Antibodies form the first line of defense and prevent the virus from invading several cells in the body. This is a protection that begins to wear over time.

But there is a second line of defense-cell-based immunity. Cells called B cells and T cells, which may take longer to produce than antibodies, provide a longer lifespan and broader protection against infection and are involved in reducing severe infections.

As a result, you may be more susceptible to mild illness after vaccination, but you are much less likely to actually get sick, be hospitalized, or die.

“But there are many reasons why people don’t want to get sick. They don’t want to give it to their loved ones. People don’t want to give it to infants who haven’t been vaccinated yet,” Falsey said. Told. ..

For months, the US Centers for Disease Control and Prevention has said that even fully vaccinated people need to continue to take precautions against infection. The room is well ventilated, wearing masks around many other people who may or may not be vaccinated, especially indoors.

The FDA is considering applying from both Moderna later this month And Johnson & Johnson Approve booster vaccination. Dr. Anthony Fauci, director of the National Institute of Infectious Diseases, said he believes that a third dose of the vaccine will be part of the standard regimen for COVID-19.

“They don’t have to attack the pharmacy and panic.”

People currently vaccinated with boosters should have been first vaccinated in January, February and March. They include people over the age of 65, adults at risk of severe illness, and people in occupations or living conditions at higher than average risk of infection.

Everyone else needs to cool it for now.

“They don’t have to panic by attacking the pharmacy,” Falsey said.

People should not be willing to take boosters because they will not get the best immune response if six months have not passed since the last dose of the Pfizer vaccine, Forch said last month at the White House. Said in the briefing.

“For example, recently vaccinated people will be tempted not to wait for six months,” Forch said. However, waiting a few months after the initial immunization to boost will help generate a stronger response. Immune system cells that help restore a weakened immune system respond more strongly if they are allowed to enter a dormant state after the first vaccination.

That said, most people need to plan to get a booster in the end, Falsey said.

“Probably applies to any vaccine, not just Pfizer. You will benefit from boosting immunity. That’s not the same as saying it’s crucially needed,” she says. I did.

People who have recovered from the infection have some protection, but vaccination provides more protection.

“I feel like I’m a strong person, so I think it’s like playing Russian roulette according to my natural immunity,” Forsy said.

Even people who look young and healthy get seriously ill with COVID-19 and die of COVID-19.

“I would never rely solely on my natural immunity to survive this virus. It’s a very, very bad actor,” Falsey said.

Is my immunity waning? Doctors advise Pfizer vaccine recipients not to worry Source link Is my immunity waning? Doctors advise Pfizer vaccine recipients not to worry

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