Moderna says the vaccine produces a promising immune response against the mutant

A doctor makes a syringe with Moderna’s vaccine.

Oliver Berg | Image Alliance | Getty Images

Booster shot ModanaThe Covid-19 vaccine produced a promising immune response against the first identified variants of B.1.351 and P.1 in South Africa and Brazil, respectively, the company announced Wednesday, in ongoing clinical trials. I quoted early data from the trial.

In this study, Moderna is testing a 50 microgram vaccine in previously vaccinated individuals. Booster doses increased the neutralizing antibody response to the original virus, as well as B.1.351 and P.1.

The company also said that booster shots of another vaccine, called mRNA-1273.351, produced an even better immune response than current vaccines against South African B.1.351 variants. The new vaccine is a variant-specific booster shot aimed at targeting B.1.351.

Preliminary results that Moderna states to be published online have not yet been peer reviewed.

“We are committed to actively working on the evolution of the virus to overcome the ongoing pandemic,” Modana CEO Stephane Bancel said in a press release. “Encouraged by these new data, we are more confident that our booster strategy should be protected from these newly discovered variants.”

Modelna said the side effects were similar to those observed after the second dose of the vaccine in a previously reported study. Side effects included pain at the injection site, malaise, headache, and muscle and joint pain.

The new data says pharmaceutical companies and scientists are likely to need booster shots of the Covid-19 vaccine and, in some cases, additional shots each year, as in the case of seasonal flu. ..

The modelna vaccine should be given twice at 4-week intervals.favorite Pfizer‘sand Johnson & JohnsonAlthough Shot is very effective against Covid, company executives and officials now say they expect strong protection to diminish over time. Pfizer’s vaccine is also a double vaccination regimen, but J & J’s vaccination is a single vaccination.

Dr. Anthony Fauci, Chief Medical Advisor at the White House, previously stated that Americans may need to take booster shots to increase protection from variants.

Last Wednesday, U.S. health officials said highly contagious variants remain “wildcards” in a national campaign to vaccinate most American adults by July 4. I did.

Centers for Disease Control and Prevention Report published on Wednesday projection COVID-19 Due to the first highly contagious B.1.1.7 mutant identified in the UK, the number of cases will increase sharply until May, and then vaccination will reduce the infection, resulting in a sharp decrease by July. Still, variants could reverse the country’s progress, officials said.

“We can see that our current vaccine protects against variants of pollutants that are prevalent in the country. Simply put, the more people who get vaccinated, the more normal they all return to normal. It will be faster, “said CDC Director Dr. Rochelle Warensky. During a press conference at White House Covid.

Moderna evaluates three approaches to boosting immunity. The first approach uses variant-specific booster shots such as mRNA-1273.351, but at a lower dose than the original vaccine. The second is to combine the original vaccine with the variant-specific vaccine into a single shot of 50 micrograms or less. The third tests the third shot of the original vaccine at a low dose.

Bansel was on CNBC last month I want a booster shot For that double vaccination available in the fall.

Moderna says the vaccine produces a promising immune response against the mutant

Source link Moderna says the vaccine produces a promising immune response against the mutant

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