If you’re a morning person, your risk of major depression may be low, new studies suggest.
Several studies of the body’s circadian sleep-wake cycle have shown that early birds are associated with a lower risk of depression. However, those studies were observational and could not prove the cause and effect.
For example, people who are early birds may have other health or lifestyle behaviors that reduce their risk of depression. You may be eating a healthier diet, for example, with more exercise or less health, such as chronic pain. depression. All these factors, and many others, may explain the reduced risk of depression rather than the fact that they are early birds. In addition, depression itself can cause sleep disorders, so depression can be the cause of staying up late, not the other way around.
However, new studies provide more compelling evidence that early to bed and early rising, independent of other factors, may provide protection against depression on their own.The· Studies published in JAMA PsychiatryUses a research method called Mendelian randomization that helps identify the cause of causality.
Mendel randomization allows researchers to compare large numbers of people based on genetic variation that does not depend on other health or behavioral characteristics. In this case, the tendency to stay up late or become a morning person inherits the characteristics randomly assigned during development. In the womb. More than 340 genetic mutations associated with circadian sleep rhythms have been identified, and researchers compare a large group of people with genetic mutations to those lacking them because they are morning people. can do. Nature, in essence, set up randomized experiments for them.
In this study, scientists used two gene databases of more than 800,000 adults to conduct a Mendelian randomized study of circadian rhythms and the risk of depression. They had not only genetic data, but also data on the diagnosis of major depression and information when people went to bed and woke up. These data were collected in both self-reported and sleep test records and used by researchers to track sleep midpoints. A useful scientific measure of someone’s sleep habits. For example, a person in the morning who goes to bed at 10am and tends to wake up at 6am will have a midpoint of sleep at 2am.
They found that people with early rising genetic variation had a 23% lower risk of major depression one hour before the midpoint of sleep.
Dr. Till Roenneberg, a chronobiologist who was not involved in the study, said that the drawback of the study is that scientists have data on when these people have to wake up for work or other obligations. He said he didn’t have it. He said Mendel’s randomization couldn’t explain the fact that the late models needed to go to work too early. It can itself contribute to depression.
“They drew the right conclusions from their data, but life is more complicated,” he said.
If you stay up late, will changing your habits reduce depression and reduce your risk of developing depression? This is not always the case, said Dr. Iyas Daghlas, a trainee at the University of California, San Francisco, who is the lead author. He said the study targeted a large number of people, not individuals.
“This data shows that certain trends in society that fall asleep later, such as using smartphones and other blue-light devices at night, may affect the level of depression in the population. “He said. .. “These results do not say that going to bed early will eliminate depression. Find out which interventions work in which population — it must be left to clinical trials.”
Still, he said: “Our data doesn’t tell you where the sweet spot is, but if you’re a night-time person, especially if you have to get up early, it’s a good idea to go to bed about an hour earlier. Safe interventions that may help with mental health. “
Morning people may have a lower risk of depression than staying up late
Source link Morning people may have a lower risk of depression than staying up late