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The FDA meeting on COVID-19 boosters may not answer all of our questions. Experts explain why – Omaha, Nebraska

Omaha, Nebraska 2021-09-21 10:25:39 –

The U.S. Food and Drug Administration is meeting on Friday for the COVID-19 vaccine booster, but the long-awaited discussion may not give an answer as to whether all vaccinated Americans will receive a third vaccination. Experts said it was sexual. Hearing opinions from the FDA Advisory Board is probably a precursor to boosting people over the age of 60. That’s because it’s where the data is most solid, “said Dr. Jonathan Reiner, CNN Medical Analyst. “The question is, what does this mean for young people, and do we need to start boosting now?” Three reports released Wednesday reported that Pfizer’s COVID-19 vaccine booster dose We support the argument that it may be needed over time. A set of data discussed by the FDA’s Vaccine Advisor, given that Pfizer required most people to approve a third booster six months after the first two vaccinations, but at this time Then it is not unanimous. .. On Monday, a group of international vaccine experts, including some from the FDA and the World Health Organization, wrote to Lancet that current evidence does not currently seem to support the need for booster shots in the general public. .. “A pretty good idea of ​​how (these meetings) go ahead,” said Sanjay Gupta, CNN’s chief medical analyst, Thursday. “I have to say, I’m not sure about this,” Gupta said, including the following unanswered questions: How serious is a breakthrough infection? How long will the booster effect last? And how much will boosters reduce infections? The question is influenced by where the United States stands in the pandemic. The proportion of the fully vaccinated population (currently about 54.2% of the total population) is much lower than experts have said. The spread of infection needs to be delayed or stopped, and cases are increasing. The advisor will review the data to balance safety and efficacy with the rise in infectious and serious illnesses facing the United States, “said Reiner. COVID-19 Pandemic Disparities Pandemics have had different impacts on different populations, but new studies show that colored races are a heavy burden. Blacks, people over the age of 40, and people with pre-existing conditions are most likely to suffer from the long Covid symptoms that affected one-third of COVID-19 patients. A study by the Department of Health and Human Services, Long Beach, California. The most common extended symptom was malaise, followed by taste and odor loss, the team reported in the Centers for Disease Control and Prevention’s Weekly Morbidity and Mortality Weekly Report. “The probability of experiencing symptoms two months after a positive SARS-CoV-2 test was significantly higher among women, those with at least one pre-existing condition, and those aged 40-54 years,” they said. wrote. Blacks showed a higher rate. Of dyspnea, joint pain, and muscle aches than other racial and ethnic groups. These results indicate that demographic disparities in extended COVID-19 symptoms need to be monitored. Racial inequality in children reflects adult inequality, according to an analysis released Thursday by the Kaiser Family Foundation. Compared to white children, the number of children’s colors has more cases, deaths, and more mental health and academic problems associated with pandemics. According to analysis, it is the most vulnerable, but less likely to be vaccinated. Hospitalization and death of COVID-19 is rare in children compared to adults, but hospitalized children are more likely to be black and Hispanic. Black and Hispanic children are also more likely to suffer from a COVID-19-related condition called MIS-C (pediatric multisystem inflammatory syndrome in children), which black children may receive intensive care. The sex was high. Alaska Native children were more likely to die of COVID-19 than white children. Fair vaccination between this group is key to achieving the whole, as children make up a significant proportion of the population and are more racially diverse than other populations. The high vaccination rate of the population may help reduce the vaccination rate gap more widely, “the report said. I breathed and talked and showed that even the simplest masks can significantly reduce infections. Our latest study provides further evidence of the importance of ai, said Dr. Don Milton, a professor of environmental health at the University of Maryland’s School of Public Health, who worked on the study. Intensive research was conducted at the University of Maryland, Walter Reed Army Research Institute, and others. Showed that people shed the virus by breathing and saliva — a finding that supports the now widely accepted idea that the virus either falls to the surface or spreads to droplets of all sizes floating in the air. They measured RNA, the most commonly used genetic material for detecting viruses. The team found that loose masks prevented about 50% of the virus-laden particles from spilling out. , It is much more infectious than Alpha and currently accounts for virtually all infectious diseases in the United States. However, the implications of the Alpha findings are clear. SARS-CoV-2 is evolving towards more efficient aerosol production and loose masks. Only provide important but modest source control. Therefore, continuous layered control and tight masks and respiratory tracts will be needed until vaccination rates are very high, “the team wrote. Alpha variant. According to our research, variants continue to be better at moving in the air, so in addition to vaccination, you need to provide better ventilation and wear a mask that fits snugly. n, to help stop the spread of the virus, “Milton said in a statement.

NS US Food and Drug Administration Meet on Friday about the COVID-19 vaccine booster, but the long-awaited discussion says that not all vaccinated Americans may be able to get an answer as to whether or not they will receive a third vaccination. The expert said.

“I think what we hear from the FDA Advisory Board is probably a go-ahead to boost people over the age of 60,” said Dr. Jonathan Reiner, CNN Medical Analyst. “The question is what does this mean for young people. Do we need to start boosting them now?”

Three reports released on Wednesday Supporting the argument that Pfizer’s COVID-19 vaccine boost may be needed over time is the data discussed by the FDA’s Vaccine Advisor seeking approval for a third boost by Pfizer. Part of the batch. People 6 months after the first two vaccinations.

However, there is no unanimous agreement so far. On Monday, a group of international vaccine experts, including some from the FDA and the World Health Organization, I wrote in The Lancet that I don’t seem to support the current evidence Currently, the general public needs booster shots.

“Usually, we have a pretty good idea of ​​how (these meetings) take place ahead of schedule,” CNN Chief Medical Analyst Sanjay Gupta said Thursday. “I have to say, I’m not sure about this.”

Gupta states that the open questions include: How serious is a breakthrough infection? How long will the booster effect last? And how much does the booster reduce transmission?

The question is influenced by where the United States stands in the pandemic.

Percentage of fully vaccinated population — Currently, it accounts for about 54.2% of the total population. — Incidents are on the rise, well below what experts have said need to slow or stop the spread.

The advisor will review the data to balance safety and efficacy with the increasing number of infectious and serious illnesses facing the United States, Reiner said.

“We want them to do this, we welcome this, but my guess is that we wouldn’t hear a kind of full opening of boosters for the whole population.” Reiner said.

COVID-19 Pandemic Disparity

New studies show that pandemics have different impacts on different populations, and colored races are under heavy burden.

Blacks, people over 40, and people with pre-existing conditions may suffer from long Covid symptoms that affected one-third of COVID-19 patients, according to a study by the California Department of Health and Human Services. The sex is the highest. ..

The most common extended symptoms were malaise, followed by taste and smell loss, the team reported in a weekly report from the Centers for Disease Control and Prevention. Weekly morbidity and mortality reports..

“The probability of experiencing symptoms two months after a positive SARS-CoV-2 test was significantly higher among women, those with at least one pre-existing condition, and those aged 40-54 years,” they said. writing.

Blacks had a higher incidence of dyspnea, joint pain, and myalgia than other racial and ethnic groups. These results indicate that demographic disparities in extended COVID-19 symptoms need to be monitored, the researchers said.

When Analysis released Thursday by the Kaiser Family Foundation Race-based disparities between children were found to reflect disparities between adults.

Compared to white children, colored children have more cases, deaths, and more pandemic-related mental health and academic problems. According to analysis, it is the most vulnerable, but less likely to be vaccinated.

Hospitalization and death of COVID-19 was rare among children compared to adults, but hospitalized children were more likely to be black and Hispanic. Black and hispanic children were more likely to suffer from a COVID-19-related condition called MIS-C (a multisystem inflammatory syndrome in children), and black children were more likely to be admitted to the intensive care unit. ..

Black, Hispanic, Native American and Alaska Native children were more likely to die of COVID-19 than white children.

“Since children make up a significant proportion of the population and are more racially diverse than other populations, fair vaccination between this group is key to achieving high vaccination rates across the population. Yes, it may help reduce vaccination disparities, and we value it more broadly. “

Masks help block airborne propagation, studies show

Meanwhile, new research Published this week Alpha variants of the coronavirus have been shown to spread more easily when people breathe and talk, but even the simplest masks have shown that infection can be significantly reduced.

“Our latest research provides further evidence of the importance of airborne transmission,” said Dr. Don Milton, a professor of environmental health at the University of Maryland’s School of Public Health.

Intensive studies conducted at the University of Maryland, the Walterreed Army Institute, and others have shown that people shed the virus from their breathing and saliva. This supports the now widely accepted belief that the virus spreads to droplets of all sizes. It may fall on the surface or float in the air. They measured RNA, the most commonly used genetic material for detecting viruses.

The team found that when the mask was loose, about 50% of the particles containing the virus did not come out.

Milton said he is currently testing what happens with the Delta variant, which is much more infectious than Alpha and currently describes virtually all infections in the United States.

However, the implications of the Alpha findings are clear.

“SARS-CoV-2 is evolving towards more efficient aerosol production, and loose masks provide important but adequate source control, so continue until vaccination rates are very high. You’ll need layered management and a snug mask and respiratory system, “the team wrote.

“Currently circulating delta variants have been found to be even more contagious than alpha variants. Our research shows that variants continue to be better at moving in the air, improving ventilation. You need to wear a mask that fits snugly. Vaccination to stop the spread of the virus. “

The FDA meeting on COVID-19 boosters may not answer all of our questions. Experts explain why Source link The FDA meeting on COVID-19 boosters may not answer all of our questions. Experts explain why

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